Mayo River Vacations from $724

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The Latest Mayo River vacation packages

Price found within the past 48 hours. Click for updated prices.
Greenwood Bed & Breakfast

Greenwood Bed & Breakfast

3 out of 5
Fisher Park
Price was $835, price is now $724 per person
$724
per person
Jun 24 - Jun 29
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Greensboro (GSO)
9.4/10 Exceptional! (58 reviews)
Breakfast was great. Parking was ideal. Safe location. Gardens around the home were lovely.

Reviewed on May 1, 2026

The Historic Magnolia House

The Historic Magnolia House

3.5 out of 5
Price was $999, price is now $741 per person
$741
per person
Jun 24 - Jun 29
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Greensboro (GSO)
6/10 (2 reviews)
Julian Price House

Julian Price House

3 out of 5
Fisher Park
Price was $923, price is now $763 per person
$763
per person
Jun 11 - Jun 14
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Greensboro (GSO)
10/10 Exceptional! (132 reviews)
Beautiful home! Not just a place to stay, but an immersive experience! We enjoyed learning about the history of this home and truly had a wonderful weekend soaking it all in. Extremely clean and expertly restored, the gardens are beautiful and the rooms take you back in time. We had everything we needed for a fabulous stay! We absolutely loved it and would stay again- this exceeded our expectations!

Reviewed on May 2, 2026

Home2 Suites by Hilton Winston-Salem Hanes Mall

Home2 Suites by Hilton Winston-Salem Hanes Mall

3 out of 5
Price was $895, price is now $779 per person
$779
per person
Jun 25 - Jun 28
found 11 hours ago
Roundtrip flight included
Philadelphia (PHL) to Greensboro (GSO)
9.2/10 Wonderful! (502 reviews)
Great stay except for one hotel associate that snapped at us for looking for coffee after dinner time in the 24/7 coffee station.

Reviewed on Mar 28, 2026

A Charming Nature Retreat

A Charming Nature Retreat

2 out of 5
Price was $890, price is now $776 per person
$776
per person
Jun 11 - Jun 14
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Greensboro (GSO)
No reviews
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Discover the most popular places to visit in Mayo River

Reynolds Homestead

Reynolds Homestead

You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forest or visit its spas.

Reynolds Homestead

Mayo River Hotel Deals

Hotel Floyd

Hotel Floyd

2 out of 5
300 Rick Lewis Way Floyd VA
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $146 total per night from May 10 to May 11
$146 total
May 10 - May 11
Total with taxes and fees
9.6/10 Exceptional! (511 reviews)
Very nice hotel with friendly staff. It’s just a short walk to the restaurants and shops, including the Floyd Country Store. The rooms were large with nice amenities and comfortable beds. Hot breakfast was good too. I’d definitely stay there again!

Reviewed on May 7, 2026

Hotel Floyd
The Lodge at Primland, Auberge Collection

The Lodge at Primland, Auberge Collection

5 out of 5
2000 Busted Rock Rd Meadows Of Dan VA
$894 nightly
The price is $1,004 total per night from May 17 to May 18
$1,004 total
May 17 - May 18
Total with taxes and fees
The Lodge at Primland, Auberge Collection
Econo Lodge Martinsville

Econo Lodge Martinsville

2 out of 5
1755 Virginia Ave Martinsville VA
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $67 total per night from May 22 to May 23
$67 total
May 22 - May 23
Total with taxes and fees
6.4/10 (506 reviews)
The front desk, Angela is very kind, friendly and professional

Reviewed on Apr 26, 2026

Econo Lodge Martinsville
See all 274 properties in Mayo River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mayo River Vacation Packages

Mayo River Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Piedmont Triad Intl. Airport (GSO)

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Frequently asked questions

How much does a Mayo River vacation package cost?
You'll find cheap prices from $724 on Expedia for your Mayo River getaway. However, a range of factors like the season, choice of hotel and length of stay will determine how much your vacation to Mayo River costs.
What are the cheapest months to go to Mayo River?
March, August and December are the best times to look for cheap Mayo River vacation packages. Choosing to travel in quieter periods means you'll typically find lower prices on flights and hotels.
How many days is enough for Mayo River?
Typically, a handful of days is enough to explore the top sights during your Mayo River vacation. However, if you prefer to have more time to chill out or go on day tours, consider extending your itinerary.
How to find the best Mayo River package deals?
Bagging a cheap Mayo River package deal is easy with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, add some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Mayo River package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a Mayo River vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll generally land a better deal than booking each component separately. And you'll still get the freedom to create a customized Mayo River vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Mayo River?
Secure incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Mayo River adventure.
How to plan a trip to Mayo River?

  1. Choose when to travel: Check your schedule and pack your bags. Your favorite time of year and the type of activities available will also help you decide when to visit Mayo River.
  2. Calculate your budget: Ensure you have enough money to cover everything from transportation and meals to experiences and flights. Your accommodations will likely be the biggest expense during your trip to Mayo River.
  3. Use our trip planning tool to discover Mayo River: Research every part of your trip to Mayo River with this handy planner. Invite your family and friends to collaborate on a group trip, search for hotels or things to do and make bookings.
  4. Set the duration of your trip: Start by listing all the attractions you'd like to experience in Mayo River. Then, estimate how long you'll need at each, as well as any travel time.
  5. Bundle your bookings: With your travel dates in order, you can combine your hotels, car rental, flights and more into a customized Mayo River vacation package.
  6. Add on excursions and experiences: Have a look at our dedicated travel guide to find some exciting things to do in Mayo River. Book tickets or make reservations as soon as you can to save time and skip the hassle of looking for activities once you arrive.

Does Expedia offer Book Now, Pay Later Mayo River vacation packages?
Set off on your dream escape to Mayo River with our Book Now, Pay Later vacations. No need to save like crazy or wait until the next payday — we've teamed up with online lender Affirm to give you more financial flexibility. Our vacation packages with payment plans allow you to spread the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, you can easily stay on budget and snap up travel deals while they last.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.