Mayo River Vacations from $454

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The Latest Mayo River vacation packages

Price found within the past 48 hours. Click for updated prices.
DoubleTree by Hilton Greensboro Airport

DoubleTree by Hilton Greensboro Airport

4 out of 5
Price was $534, price is now $454 per person
$454
per person
Aug 6 - Aug 10
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Greensboro (GSO)
8.8/10 Excellent! (1,280 reviews)
1) I was not provided the room that I requested. 2) The shower gel/soap was empty, which I discovered while I was in the shower. 3) The bathroom wall was not clean

Reviewed on Jun 28, 2026

Julian Price House

Julian Price House

3 out of 5
Fisher Park
Price was $927, price is now $668 per person
$668
per person
Jul 30 - Aug 2
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Greensboro (GSO)
10/10 Exceptional! (139 reviews)
If a traveler is one who can appreciate wonderful history of a given area within any town, who marvels at the architecture of the early 1900's, who respects the work to refurbish and maintain a nearly 100 year old home, is charmed by the landscape and relishes calm, civility and old luxury........this is the place to stay. Sans a few quirks, we thoroughly enjoyed our stay and felt transported back to the roaring '20's. The only think they we would have liked to have enjoyed, was a breakfast vs a continental menu. We met one of the owners and he was gracious with his time and key historical notes regarding the house and previous owners.

Reviewed on Jun 29, 2026

Arcade Kid Friendly Firepit Grill HotTub

Arcade Kid Friendly Firepit Grill HotTub

4 out of 5
Save 100% on your flight
Price was $1,821, price is now $1,452 per person
$1,452
per person
Aug 6 - Aug 10
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Greensboro (GSO)
No reviews
O.Henry Hotel

O.Henry Hotel

4 out of 5
Price was $687, price is now $585 per person
$585
per person
Sep 18 - Sep 20
found 1 day ago
Roundtrip flight included
New York (NYC) to Greensboro (GSO)
9.8/10 Exceptional! (819 reviews)
We had an excellent stay the O.Henry Hotel. The bed was comfortable and the room was clean. The staff were very helpful and friendly. The Bose sound system in the room was an added bonus. I would definitely be willing to stay here again when in the area.

Reviewed on Jun 29, 2026

Wyndham Garden Greensboro

Wyndham Garden Greensboro

3 out of 5
Price was $599, price is now $510 per person
$510
per person
Aug 6 - Aug 10
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Greensboro (GSO)
7.8/10 Good! (1,074 reviews)
Clean room. Great breakfast.

Reviewed on Jun 29, 2026

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Stay near popular Mayo River attractions

Reynolds Homestead

You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forest or visit its spas.
See properties

Mayo River Hotel Deals

The Lodge at Primland, Auberge Collection

The Lodge at Primland, Auberge Collection

5 out of 5
2000 Busted Rock Rd Meadows Of Dan VA
Get rates
The Lodge at Primland, Auberge Collection
Hampton Inn Eden

Hampton Inn Eden

2.5 out of 5
724 S Van Buren Rd Eden NC
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $137 total per night from Jul 12 to Jul 13
$137 total
Jul 12 - Jul 13
Total with taxes and fees
8.6/10 Excellent! (464 reviews)
"Awesome staff, good breakfast, a great place to stay. I recommend it highly Exterior needs a little TLC. Other than that it was a great stay"

Reviewed on Jun 28, 2026

Hampton Inn Eden
Comfort Inn Martinsville

Comfort Inn Martinsville

3 out of 5
378 Commonwealth Blvd W Martinsville VA
Fully refundable
$117 nightly
The price is $132 total per night from Jul 26 to Jul 27
$132 total
Jul 26 - Jul 27
Total with taxes and fees
6.8/10 (676 reviews)
"Walked up to the entrance and you had to manually slide the door open and shut it behind you. The second door was the same way. The staff was a hoot. I get to my room and discover that there was no refrigerator. The light switch for the bathroom was messed up so you had to jiggle it to get the light ..."

Reviewed on Jun 28, 2026

Comfort Inn Martinsville
See all 272 properties in Mayo River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mayo River Vacation Packages

Mayo River Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Piedmont Triad Intl. Airport (GSO)

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Frequently asked questions

How much does a Mayo River vacation package cost?
You'll find cheap prices from $454 on Expedia for your Mayo River getaway. However, a range of factors like the season, choice of hotel and length of stay will determine how much your vacation to Mayo River costs.
What are the cheapest months to go to Mayo River?
March, August and December are the best times to look for cheap Mayo River vacation packages. Choosing to travel in quieter periods means you'll typically find lower prices on flights and hotels.
How many days is enough for Mayo River?
Typically, a handful of days is enough to explore the top sights during your Mayo River vacation. However, if you prefer to have more time to chill out or go on day tours, consider extending your itinerary.
How to find the best Mayo River package deals?
Bagging a cheap Mayo River package deal is easy with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, add some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Mayo River package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a Mayo River vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll generally land a better deal than booking each component separately. And you'll still get the freedom to create a customized Mayo River vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Mayo River?
Secure incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Mayo River adventure.
How to plan a trip to Mayo River?

  1. Choose when to travel: Check your schedule and pack your bags. Your favorite time of year and the type of activities available will also help you decide when to visit Mayo River.
  2. Calculate your budget: Ensure you have enough money to cover everything from transportation and meals to experiences and flights. Your accommodations will likely be the biggest expense during your trip to Mayo River.
  3. Use our trip planning tool to discover Mayo River: Research every part of your trip to Mayo River with this handy planner. Invite your family and friends to collaborate on a group trip, search for hotels or things to do and make bookings.
  4. Set the duration of your trip: Start by listing all the attractions you'd like to experience in Mayo River. Then, estimate how long you'll need at each, as well as any travel time.
  5. Bundle your bookings: With your travel dates in order, you can combine your hotels, car rental, flights and more into a customized Mayo River vacation package.
  6. Add on excursions and experiences: Have a look at our dedicated travel guide to find some exciting things to do in Mayo River. Book tickets or make reservations as soon as you can to save time and skip the hassle of looking for activities once you arrive.

Does Expedia offer Book Now, Pay Later Mayo River vacation packages?
Set off on your dream escape to Mayo River with our Book Now, Pay Later vacations. No need to save like crazy or wait until the next payday — we've teamed up with online lender Affirm to give you more financial flexibility. Our vacation packages with payment plans allow you to spread the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, you can easily stay on budget and snap up travel deals while they last.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.