Mayo River Vacations from $338

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The Latest Mayo River vacation packages

Price found within the past 48 hours. Click for updated prices.
Hawthorne Inn and Conference Center

Hawthorne Inn and Conference Center

3 out of 5
per person
Oct 17 - Oct 19
found 1 day ago
Roundtrip flight included
New York (NYC) to Greensboro (GSO)
8.2/10 Very Good! (1,001 reviews)
Close to Carolina University

Reviewed on Aug 16, 2025

Julian Price House

Julian Price House

3 out of 5
Fisher Park
per person
Oct 17 - Oct 19
found 1 day ago
Roundtrip flight included
New York (NYC) to Greensboro (GSO)
10/10 Exceptional! (102 reviews)
The staff was very detailed and organized with my arrival being that I flew in from KY at midnight. The interior and exterior design is EXQUISITE! My communication with the staff was always very pleasant and professional via text. I will be booking another stay the next time I’m in NC.

Reviewed on Aug 15, 2025

O.Henry Hotel

O.Henry Hotel

4 out of 5
per person
Oct 17 - Oct 19
found 1 day ago
Roundtrip flight included
New York (NYC) to Greensboro (GSO)
9.8/10 Exceptional! (685 reviews)
The design of the hotel and the special events like Jazz night and Tea in the afternoon were a delight.

Reviewed on Jul 21, 2025

La Quinta Inn & Suites by Wyndham Winston-Salem

La Quinta Inn & Suites by Wyndham Winston-Salem

3 out of 5
per person
Oct 17 - Oct 19
found 1 day ago
Roundtrip flight included
New York (NYC) to Greensboro (GSO)
7/10 Good! (1,002 reviews)
No issues whatsoever. Great staff.

Reviewed on Jul 22, 2025

Proximity Hotel

Proximity Hotel

4 out of 5
per person
Oct 17 - Oct 19
found 1 day ago
Roundtrip flight included
New York (NYC) to Greensboro (GSO)
9.6/10 Exceptional! (832 reviews)
Great staff. Excellent service. Great food.

Reviewed on Aug 4, 2025

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Discover the most popular places to visit in Mayo River

The Reynolds Homestead, built in 1943 is in a beautiful foothill setting. Hardin Reynolds and his wife produced 16 children here, the most famous being RJ Reynolds who migrated to Winston Salem, NC to start the tobacco empire of the same name. The catalpa tree in the foreground still remains from the earliest days of the homestead.

Reynolds Homestead

You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forest or visit its spas.

Reynolds Homestead

Mayo River Hotel Deals

Primland Resort, Auberge Resorts Collection

Primland Resort, Auberge Resorts Collection

5 out of 5
2000 Busted Rock Rd, Meadows Of Dan, VA
$626 nightly
The price is $697 total per night from Sep 1 to Sep 2
$697 total
Sep 1 - Sep 2
Total includes taxes and fees
8.8/10 Excellent! (23 reviews)
The Primland Resort is second to none.
"Our first stay at Primland Resort was beautiful, peaceful, and fun. Our second honeymoon after 20 years was better than our first. The Service was wonderful, the food, impeccable, we had privacy, yet met many wonderful people. We will be back!"

Reviewed on Mar 13, 2025

Primland Resort, Auberge Resorts Collection
Hampton Inn Eden

Hampton Inn Eden

2.5 out of 5
724 S Van Buren Rd, Eden, NC
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $129 total per night from Sep 12 to Sep 13
$129 total
Sep 12 - Sep 13
Total includes taxes and fees
8.6/10 Excellent! (412 reviews)
Great stay in Eden!
"Hotel was clean and comfortable. Great stay."

Reviewed on Aug 13, 2025

Hampton Inn Eden
Baymont by Wyndham Eden

Baymont by Wyndham Eden

2.5 out of 5
716 Linden Dr, Eden, NC
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $125 total per night from Aug 31 to Sep 1
$125 total
Aug 31 - Sep 1
Total includes taxes and fees
8.4/10 Very Good! (512 reviews)
"We arrived late, after 10pm, desperate for a room because our original booking was disgusting and we had to leave. We were greeted instantly, a room was available immediately, it was cool, clean and exactly what we needed. We felt safe and comfortable and we are so very thankful!"

Reviewed on Jul 28, 2025

Baymont by Wyndham Eden
See all 278 properties in Mayo River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Mayo River vacation package cost?
You'll find cheap prices from $338 on Expedia for your Mayo River getaway. However, a range of factors like the season, choice of hotel and length of stay will determine how much your vacation to Mayo River costs.
What are the cheapest months to go to Mayo River?
March, August and December are the best times to look for cheap Mayo River vacation packages. Choosing to travel in quieter periods means you'll typically find lower prices on flights and hotels.
How many days is enough for Mayo River?
Typically, a handful of days is enough to explore the top sights during your Mayo River vacation. However, if you prefer to have more time to chill out or go on day tours, consider extending your itinerary.
How to find the best Mayo River package deals?
Bagging a cheap Mayo River package deal is easy with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, add some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Mayo River package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a Mayo River vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll generally land a better deal than booking each component separately. And you'll still get the freedom to create a customized Mayo River vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Mayo River?
Secure incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Mayo River adventure.
How to plan a trip to Mayo River?

  1. Choose when to travel: Check your schedule and pack your bags. Your favorite time of year and the type of activities available will also help you decide when to visit Mayo River.
  2. Calculate your budget: Ensure you have enough money to cover everything from transportation and meals to experiences and flights. Your accommodations will likely be the biggest expense during your trip to Mayo River.
  3. Use our trip planning tool to discover Mayo River: Research every part of your trip to Mayo River with this handy planner. Invite your family and friends to collaborate on a group trip, search for hotels or things to do and make bookings.
  4. Set the duration of your trip: Start by listing all the attractions you'd like to experience in Mayo River. Then, estimate how long you'll need at each, as well as any travel time.
  5. Bundle your bookings: With your travel dates in order, you can combine your hotels, car rental, flights and more into a customized Mayo River vacation package.
  6. Add on excursions and experiences: Have a look at our dedicated travel guide to find some exciting things to do in Mayo River. Book tickets or make reservations as soon as you can to save time and skip the hassle of looking for activities once you arrive.

Does Expedia offer Book Now, Pay Later Mayo River vacation packages?
Set off on your dream escape to Mayo River with our Book Now, Pay Later vacations. No need to save like crazy or wait until the next payday — we've teamed up with online lender Affirm to give you more financial flexibility. Our vacation packages with payment plans allow you to spread the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, you can easily stay on budget and snap up travel deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.