Title: Mayo River Vacation Packages 2026 from $382 | Expedia.com [Mayo River Travel Guide](https://expedia.com/Mayo-River.dx553248635976006279)[Hotels in Mayo River](https://expedia.com/Mayo-River-Hotels.d553248635976006279.Travel-Guide-Hotels)[Vacation Rentals in Mayo River](https://expedia.com/Mayo-River-Vacation-Rentals.d553248635976006279.Travel-Guide-VacationRentals)[Flights to Mayo River](https://expedia.com/Cheap-Flights-To-Mayo-River.d553248635976006279.Travel-Guide-Flights)[Car Rentals in Mayo River](https://expedia.com/Car-Rentals-In-Mayo-River.d553248635976006279.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Mayo River Vacations from $382 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## The Latest Mayo River vacation packages Price found within the past 48 hours. Click for updated prices. ![OYO Inn Kernersville](https://images.trvl-media.com/lodging/38000000/37410000/37406200/37406110/88e5a72c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### OYO Inn Kernersville $382 per person May 21 - May 26 found 16 hours ago Roundtrip non-stop flight included New York (LGA) to Greensboro (GSO) 7/10 Good! (369 reviews) Room was fine for price the price they asked at hotel was too high but water was very hot and was great for shower...book online for a decent rate Reviewed on Jan 6, 2026 ![The Inn at Elon](https://images.trvl-media.com/lodging/41000000/40350000/40340600/40340539/215ba6d2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Inn at Elon Save 100% on your flight $569 per person May 1 - May 4 found 7 hours ago Roundtrip flight included New York (NYC) to Greensboro (GSO) 9.6/10 Exceptional! (617 reviews) The staff at the hotel were all very courteous and kind. The rooms were immaculate and well kept. Our breakfast was excellent and the service was even better. We were thrilled with the experience and value of the Inn at Elon Reviewed on Feb 22, 2026 ![The Historic Magnolia House](https://images.trvl-media.com/lodging/73000000/72470000/72464600/72464524/5580fe60_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Historic Magnolia House $451 per person May 1 - May 4 found 7 hours ago Roundtrip flight included New York (NYC) to Greensboro (GSO) 6/10 (2 reviews) ![Dailey Renewal Retreat Bed & Breakfast](https://images.trvl-media.com/lodging/4000000/3980000/3979300/3979281/3551644d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Dailey Renewal Retreat Bed & Breakfast Lindley Park $522 per person Mar 31 - Apr 4 found 6 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Greensboro (GSO) 9/10 Wonderful! (207 reviews) This place will always be near and dear to my heart. The breakfast was absolutely delicious, the atmosphere was so cozy and loving I did not want to leave. It was a pleasure to meet Miss Jean Dailey and I hope to come back some time soon. Plus, the house is surrounded by some VERY delicious options for food. If you’re looking for a home-away-from-home getaway, that actually isn’t in the middle of nowhere, I highly recommend! Reviewed on Aug 5, 2025 ![Best Western Greensboro Coliseum Inn](https://images.trvl-media.com/lodging/1000000/20000/12600/12540/d47d458c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Best Western Greensboro Coliseum Inn $412 per person Apr 16 - Apr 21 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Greensboro (GSO) 7.8/10 Good! (93 reviews) Everything was awesome Reviewed on Feb 27, 2026 Don't see what you're looking for? See all available trips from Columbus to Mayo River [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-01/2026-04-08/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=GSO&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_553248635976006279) ### Discover the most popular places to visit in Mayo River ![The Reynolds Homestead, built in 1943 is in a beautiful foothill setting. Hardin Reynolds and his wife produced 16 children here, the most famous being RJ Reynolds who migrated to Winston Salem, NC to start the tobacco empire of the same name. The catalpa tree in the foreground still remains from the earliest days of the homestead.](https://images.trvl-media.com/place/553248621561864249/54558157-d5bc-4ba5-a77d-f9a917492c5a.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Reynolds Homestead You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forest or visit its spas. [](https://expedia.com/Reynolds-Homestead-Patrick-Springs.d553248621561864249.Vacation-Attraction) ## Mayo River Hotel Deals ![The Lodge at Primland, Auberge Collection](https://images.trvl-media.com/lodging/4000000/3640000/3633200/3633184/d7ce6da6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Lodge at Primland, Auberge Collection 2000 Busted Rock Rd Meadows Of Dan VA $490 nightly $550 total Mar 2 - Mar 3 Total with taxes and fees 9.2/10 Wonderful! (27 reviews) Very courteous staff, lovely accommodations, can't wait to return! Reviewed on Feb 22, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F2%2F2026&endDate=3%2F3%2F2026&selected=3633184&PinnedHotelID=3633184&HadPinnedHotel=true®ionId=553248635976006279) ![Comfort Inn Martinsville](https://images.trvl-media.com/lodging/1000000/670000/665100/665072/5a1d33a7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Inn Martinsville 378 Commonwealth Blvd W Martinsville VA Fully refundableReserve now, pay when you stay $108 nightly $122 total Mar 8 - Mar 9 Total with taxes and fees 6.8/10 (631 reviews) Such kind service and large variety for breakfast! Our sports team had a lovely stay here Reviewed on Mar 1, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=665072&PinnedHotelID=665072&HadPinnedHotel=true®ionId=553248635976006279) ![Baymont by Wyndham Eden](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/34cebbf3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Baymont by Wyndham Eden 716 Linden Dr Eden NC Fully refundableReserve now, pay when you stay $84 nightly $94 total Mar 8 - Mar 9 Total with taxes and fees 8.6/10 Excellent! (576 reviews) The room was very clean. Check in and out was quick and easy. The only issue I had was that the breakfast was pretty well cleaned out at 9:00 am. Reviewed on Feb 23, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=570926&PinnedHotelID=570926&HadPinnedHotel=true®ionId=553248635976006279) [See all 271 properties in Mayo River](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F2%2F2026&endDate=3%2F3%2F2026®ionId=553248635976006279) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Mayo River Vacation Packages ## Mayo River Essential Information | Language | English | | --------------- | ---------------------------------- | | Currency | U.S dollars | | Closest Airport | Piedmont Triad Intl. Airport (GSO) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) 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[](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ## Frequently asked questions ### How much does a Mayo River vacation package cost? ### What are the cheapest months to go to Mayo River? ### How many days is enough for Mayo River? ### How to find the best Mayo River package deals? ### Is it cheaper to book a Mayo River vacation as a package? ### When to book a vacation package to Mayo River? ### How to plan a trip to Mayo River? > 1. Choose when to travel: Check your schedule and pack your bags. Your favorite time of year and the type of activities available will also help you decide when to visit Mayo River. > 2. Calculate your budget: Ensure you have enough money to cover everything from transportation and meals to experiences and flights. Your accommodations will likely be the biggest expense during your trip to Mayo River. > 3. Use our [trip planning tool](https://www.expedia.com/why/trip-planning) to discover Mayo River: Research every part of your trip to Mayo River with this handy planner. Invite your family and friends to collaborate on a group trip, search for hotels or things to do and make bookings. > 4. Set the duration of your trip: Start by listing all the attractions you'd like to experience in Mayo River. Then, estimate how long you'll need at each, as well as any travel time. > 5. Bundle your bookings: With your travel dates in order, you can combine your hotels, car rental, flights and more into a customized Mayo River vacation package. > 6. Add on excursions and experiences: Have a look at our dedicated travel guide to find some exciting [things to do](https://www.expedia.com/Activities) in Mayo River. Book tickets or make reservations as soon as you can to save time and skip the hassle of looking for activities once you arrive. ### Does Expedia offer Book Now, Pay Later Mayo River vacation packages? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Critz Hotels ](https://www.expedia.com/Critz-Hotels.d6351114.Travel-Guide-Hotels) - [Cabin Rentals in Critz ](https://www.expedia.com/Critz-Cabins.d6351114-aaCabins.Travel-Guide-Accommodation) - [B&B in Critz ](https://www.expedia.com/Critz-Bed-And-Breakfast.d6351114-aaBedAndBreakfast.Travel-Guide-Accommodation) - [3 Star Hotels in Critz ](https://www.expedia.com/3Star-Critz-Hotels.s30-0-d6351114.Travel-Guide-Filter-Hotels) - [Vacation Homes in Critz ](https://www.expedia.com/Critz-Private-Vacation-Homes.d6351114-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Patrick Springs Hotels ](https://www.expedia.com/Patrick-Springs-Hotels.d3000460602.Travel-Guide-Hotels) - [Cabin Rentals in Patrick Springs ](https://www.expedia.com/Patrick-Springs-Cabins.d3000460602-aaCabins.Travel-Guide-Accommodation) - 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